La Reina

La Reina is the mezcal and tequila bar inside El Rey Court on Cerrillos Road, and it doubles as Santa Fe's most reliable LGBTQ+ nightlife anchor. Every Monday evening it hosts Queer Night, an intentionally LGBTQ+-centered gathering that draws a mixed local crowd and channels support to the Transgender Resource Center of New Mexico. The bar leans into Oaxacan agave spirits, natural wine and a relaxed, design-forward Southwestern setting rather than a big-club atmosphere — which fits a city whose queer social life runs through recurring nights and community events more than through dedicated gay bars. Expect a low-key, welcoming room, courtyard seating in warm months, and a crowd that mixes hotel guests, locals and visitors.